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Stem cells treatment for wilson disease

Author(s):

Shan Tang, Li Bai, Zhongping Duan and Sujun zheng*  

Abstract:


Wilson disease (WD) is a copper excretion disorder, mainly caused by mutations in the ATP7B gene. Pharmacological therapies and liver transplantation are currently the main treatment methods for WD, but they face problems such as drug treatment compliance, adverse reactions, and shortage of liver donors. Stem cell therapy of WD may correct abnormal copper metabolism permanently, which is the focus of current research. In this review, we summarized the latest research on stem cells treatment for WD, as well as current challenges and future expectations.

Keywords:

Stem cells, liver disease, stem cell-based therapy, Wilson disease, treatment, regeneration

Affiliation:

The First Unit, Department of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing, The Fourth Unit, Department of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing, The Fourth Unit, Department of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing, The First Unit, Department of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing



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