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Application of Stem Cell Therapy during the treatment of HIV/AIDS and Duchenne Muscular Dystrophy

Author(s):

Lorraine Chitena, Keletso Masisi, Kabo Masisi, Tebogo E. Kwape and Goabaone Gaobotse*  

Abstract:


Treating diseases such as Muscular dystrophy (MD) and HIV/AIDS poses several challenges to the rapidly evolving field of regenerative medicine. Previously, stem cell therapy has been said to affect the clinical courses of HIV/AIDS and MD, but, in practice, eradication or control of these diseases was not achievable. The introduction of gene editing into stem cell therapy has stimulated HIV/AIDS and MD cell therapy research studies substantially. Here, we review current methods of treating HIV/AIDS and MD using stem cell therapy. This review also details the use of different types of cells and methods in cell therapy and the modeling of new cell-based therapies to treat Duchenne muscular dystrophy. We speculate that the effective use stem cell therapy in conjunction with other treatment therapies such as steroids and rehabilitation could improve livelihood.

Keywords:

High active antiretroviral therapy, C-C chemokine receptor 5, Antiretroviral treatment, Pre-exposure prophylaxis, Hematopoietic stem cells, Induced pluripotent stem cells, Muscular dystrophy, Duchenne muscular dystrophy, Melancholy stem cells

Affiliation:

Department of Biological Sciences and Biotechnology, Botswana International University of Science and Technology, Private Bag 16, Palapye, Department of Biological Sciences and Biotechnology, Botswana International University of Science and Technology, Private Bag 16, Palapye, Department of Biological Sciences and Biotechnology, Botswana International University of Science and Technology, Private Bag 16, Palapye, Department of Biological Sciences and Biotechnology, Botswana International University of Science and Technology, Private Bag 16, Palapye, Department of Biological Sciences and Biotechnology, Botswana International University of Science and Technology, Private Bag 16, Palapye



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