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Recent Biomedical Applications on Stem Cell Therapy: A Brief Overview

[ Vol. 14 , Issue. 2 ]

Author(s):

Mukta Agrawal, Amit Alexander*, Junaid Khan, Tapan Kumar Giri, Sabahuddin Siddique, Sunil Kumar Dubey, Ajazuddin, Ravish J Patel, Umesh Gupta, Swarnlata Saraf and Shailendra Saraf   Pages 127 - 136 ( 10 )

Abstract:


Stem cells are the specialized cell population with unique self-renewal ability and act as the precursor of all the body cells. Broadly, stem cells are of two types one is embryonic stem cells while the other is adult or somatic stem cells. Embryonic stem cells are the cells of zygote of the blastocyst which give rise to all kind of body cells including embryonic cells, and it can reconstruct a complete organism. While the adult stem cells have limited differentiation ability in comparison with embryonic stem cells and it proliferates into some specific kind of cells. This unique ability of the stem cell makes it a compelling biomedical and therapeutic tool. Stem cells primarily serve as regenerative medicine for particular tissue regeneration or the whole organ regeneration in any physical injury or disease condition (like diabetes, cancer, periodontal disorder, etc.), tissue grafting and plastic surgery, etc. Along with this, it is also used in various preclinical and clinical investigations, biomedical engineering and as a potential diagnostic tool (such as the development of biomarkers) for non-invasive diagnosis of severe disorders. In this review article, we have summarized the application of stem cell as regenerative medicine and in the treatment of various chronic diseases.

Keywords:

Stem cell, regenerative medicine, human embryonic stem cell, pluripotent stem cell, bone regeneration, heart regeneration.

Affiliation:

Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, University Teaching Department (Pharmacy), Sarguja University, Ambikapur (Chhattisgarh), NSHM College of Pharmaceutical Technology, NSHM Knowledge Campus, Kolkata Group of Institutions, 124 BL Saha Road, Kolkata-700 053, West Bengal, Patel College of Pharmacy, Madhyanchal Professional University, Bhopal, Madhya Pradesh, Department of Pharmacy, Birla Institute of Technology and Science, Pilani (BITS-PILANI), Pilani Campus, Rajasthan, Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, Ramanbhai Patel College of Pharmacy (RPCP), Charotar University of Science and Technology (CHARUSAT), Gujarat, Department of Pharmacy, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Bandarsindri, Kishangarh, Ajmer – 305817, University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, Durg University, Govt. Vasudev Vaman Patankar Girls’ P.G. College Campus, Raipur Naka, Durg, Chhattisgarh



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