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Electrospun Fibers for Cartilage Tissue Regeneration

[ Vol. 13 , Issue. 7 ]

Author(s):

Guo Li, Sirong Shi, Shiyu Lin, Tengfei Zhou, Xiaoru Shao, Qiao Huang, Bofeng Zhu and Xiaoxiao Cai*   Pages 591 - 599 ( 9 )

Abstract:


Background: Cartilage injury has always been puzzled for clinicians. The treatments used clinically for cartilage injury usually bring about fibrocartilage. The emergence of tissue engineering lights up the hope of cartilage repair.

Objective: This review will sum up the existing learnings about electrospun fibers, revolving about the electrospinning materials, micromorphology, improvements and electrospun technologies newly developed in cartilage repair and regeneration.

Results: Electrospun fibers as scaffolds for cartilage regeneration have been one of researching hotspots for years. The studies about new electrospun materials and new electrospinning technologies greatly promoted the development of this field.

Conclusion: Electrospun fibers have showed great potential in cartilage regeneration. But there is still a long way to go before clinical application. The material embellishment and structure imitation should be highlighted in future.

Keywords:

Electrospun, tissue engineering, electrospinning materials, stem cell, biomaterials, cartilage.

Affiliation:

State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi’an Jiaotong University, Xi’an 710004, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu



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