Shibashish Giri and Augustinus Bader Pages 692 - 705 ( 14 )
Regeneration of diseased organ is a ubiquitous clinical need. The clinical utilities of adult stem cells and microRNA have become a promising strategy for treatment of a number disease. This review aims to highlight the current clinical evidence of personalized and regenerative therapy for diseases like liver which could revolutionize patient care in the near future at a global scale. Herein, we explain the importance of personalized and regenerative medicine for bedside (intraoperative) in situ and In vivo regeneration of damaged organ/ tissues that is now being transferred to a larger field of clinical applications in a novel translational approach.
Adult stem cells, bioartificial liver, bioreactor, decellularization, induced pluripotent stem cells technology, recellularization, stem cell activation.
Applied Stem Cell Biology and Cell Technology, Biomedical and Biotechnological Center (BBZ), Medical faculty, Universität Leipzig, Deutscher Platz 5, D-04103 Leipzig, Germany.