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Article Details


Personalized and Regenerative Medicine for Liver Diseases

[ Vol. 11 , Issue. 8 ]

Author(s):

Shibashish Giri and Augustinus Bader   Pages 692 - 705 ( 14 )

Abstract:


Regeneration of diseased organ is a ubiquitous clinical need. The clinical utilities of adult stem cells and microRNA have become a promising strategy for treatment of a number disease. This review aims to highlight the current clinical evidence of personalized and regenerative therapy for diseases like liver which could revolutionize patient care in the near future at a global scale. Herein, we explain the importance of personalized and regenerative medicine for bedside (intraoperative) in situ and In vivo regeneration of damaged organ/ tissues that is now being transferred to a larger field of clinical applications in a novel translational approach.

Keywords:

Adult stem cells, bioartificial liver, bioreactor, decellularization, induced pluripotent stem cells technology, recellularization, stem cell activation.

Affiliation:

Applied Stem Cell Biology and Cell Technology, Biomedical and Biotechnological Center (BBZ), Medical faculty, Universit├Ąt Leipzig, Deutscher Platz 5, D-04103 Leipzig, Germany.



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